Types of Capsules in Pharmacy: Exploring Formulation Techniques

July 19, 2023

Pharmaceuticals and the dietary supplement industry have evolved dramatically over the years, and one of the most prominent advancements lies in the formulation of medication and supplements. Enter the world of capsules, a versatile and widely used dosage form that caters to various applications across industries. The types of capsules used in pharmacies and health and wellness stores significantly impact the delivery, absorption, and effectiveness of drugs or dietary supplements, offering innovative solutions for both producers and consumers.

Types of Capsules and Their Importance in Pharmacy

Capsules, primarily known for their ease of swallowing and accurate dosage capabilities, come in various types. Each caters to specific needs and applications, making it essential to understand the types of capsules in pharmacy and their respective attributes.

  • Two-Piece Empty Hard Capsules: These are the most common types of capsules, comprising two pieces that fit into each other. These are ideal for both solid and liquid drug or supplement encapsulation, providing accurate dosage administration and protection of active ingredients.
  • Vegan Capsules: With the growing demand for natural and sustainable products, the pharmaceutical industry has seen an increased utilization of plant-based or vegan capsules. Made from polysaccharide polymers like pullulan or hydroxypropyl methylcellulose (HPMC), these capsules offer high performance, versatility, and align with clean-label or plant-based requirements.
  • Capsules with Improved Dissolution Profiles: Advancements in capsule technology have led to the development of capsules with better bioavailability and controlled release of active ingredients. These enhanced capsules range from enteric-coated and gastro-resistant to those with modified release properties, enabling targeted drug delivery and improved patient compliance.
  • Capsule-in-Capsule Technology: A next-level solution offering unparalleled customization and endless innovation potential. These capsules allow unique combinations of multiple ingredients with customizable release profiles, packed into one convenient dose.

Understanding these different kinds of capsules allows professionals to make informed decisions based on the formulation’s requirements, whether it’s for pharmaceutical applications or dietary supplement production. As a result, it leads to more efficacious, consumer-friendly products that meet the shifting needs of the market.

In the next section, we’ll delve into the current market trends and innovations in the capsule industry.

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Current Market Trends and Innovations in the Capsule Industry

As the dietary supplement and pharmaceutical industries continuously evolve, so too does the market for two-piece empty hard capsules. Let’s dive into the latest trends and innovations that are revolutionizing this sector.

  • Increased Demand for Plant-based Capsules: A significant trend in recent years is the shift towards vegan, plant-based capsules, largely due to the rising demand for natural and sustainable products. Brands can now opt for high-performance materials like pullulan and hydroxypropyl methylcellulose (HPMC), which are not only plant-based but also have high performance and versatility.
  • Advancements in Capsule Design: Innovation is key in the capsule market. The advent of enteric-coated, gastro-resistant, and modified-release capsules has dramatically transformed the pharmaceutical and nutraceutical landscape. Such advancements facilitate targeted drug delivery, improving patient compliance and satisfaction.
  • Capsule-in-Capsule Technology: This solution offers next-level customization. By encapsulating liquids or powders in an inner capsule with a liquid-filled outer capsule, it enables unique combinations of multiple ingredients, creating tailored release profiles in one convenient dose.

These innovations are more than just trends – they’re the driving force shaping the future of the capsule industry.

Capsule Advantages and Disadvantages

Like any dosage form, capsules come with their own set of advantages and disadvantages. Understanding these can help us make informed decisions when choosing between different types of capsules.

Advantages:

  • Ease of Swallowing: Capsules are generally easier to swallow than tablets, making them more user-friendly, especially for those who struggle with tablet ingestion.
  • Fast Action: Capsules disintegrate rapidly once inside the body, releasing the drug faster than tablets.
  • Tasteless: Capsules are tasteless, providing an excellent option for drugs with an unpleasant taste or odor.

Disadvantages:

  • Cost: Capsules can be a bit more expensive to manufacture than tablets.
  • Dosage Limitations: Capsules have limited space and cannot accommodate very high dosages.
  • Cannot be Split: Unlike tablets, capsules cannot be split into smaller doses.

Despite these limitations, the benefits of capsules often outweigh the disadvantages, making them a popular choice in both the pharmaceutical and dietary supplement industries.

Remember, choosing the right form of dosage depends on various factors, including the type of drug or dietary supplement, its dosage, and the targeted consumer base. At VBC, we pride ourselves on our facility and experienced teams that can guide you every step of the way in your capsule manufacturing journey.

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Expanding Applications of Capsules in Various Industries

Two-piece empty hard capsules have found extensive applications across different sectors. These types of capsules in pharmacy, nutraceuticals, and other related industries have brought about revolutionary changes in the delivery of active ingredients.

Pharmaceutical Industry: The pharmaceutical sector utilizes these capsules to deliver both solid and liquid drugs, providing precise dosage administration and superior protection of active ingredients. From everyday pain relievers to complex medications, capsules have become a primary choice for medicine delivery.

Nutraceutical Sector: The use of two-piece empty hard capsules is also prolific in the nutraceutical industry. Here, they encapsulate dietary supplements, vitamins, herbal extracts, and probiotics, ensuring optimal product integrity and stability.

Capsule-in-capsule technology and acid-protection designed-release capsule technology are game-changing solutions that continue to push the boundaries of innovation in these industries. By allowing unique combinations of multiple ingredients with customizable release profiles or helping to protect sensitive ingredients, capsules provide an efficacious and user-friendly solution.

The Future: Next-Generation Supplement Design and Synergistic Solutions

The future of the supplement industry is already taking shape, and capsules play a significant role in that future. One exciting development involves an enhancement of the sensory experience to encourage compliance and repeat purchases.

Aesthetics Matter: Consumers increasingly favor supplements that offer a visually appealing experience. For example, 30% of consumers are likely to purchase supplements with coloring (Source: NMI 2020 SORD – U.S.). Brands can now create bright white capsules without the use of traditional additives like titanium dioxide (TiO2), which was recently classified as an unsafe food additive. Instead, plant-based capsules can be tinted with natural ingredients like purple carrot and blue spirulina to create eye-catching supplements.

Flavor and Aroma Coatings: The future of capsule technology also involves the use of flavor and aroma coatings, created using naturally derived essential oils. These not only stimulate the senses but can be used to convey specific associations, like using lavender coatings on purple-colored capsules for products supporting sleep or stress.

At VBC, we understand the complexities of consumer expectations. With rapid supplement innovation, there’s no need to choose between consumer experience and an efficacious product. We can ensure you deliver on both fronts. For more details about our capsule manufacturing processes, visit our capsule manufacturing page.

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Synergistic Partnership

From the countless kinds of capsules available to the ongoing advancements in capsule technology, this delivery method offers brands a host of opportunities. Whether you’re aiming for a clean-label, plant-based product or looking to deliver a complex formulation, the different types of capsules in pharmacy and nutraceutical applications can meet diverse consumer needs.

At VBC, we pride ourselves on being a leading toll manufacturer in the Philippines. Our team is equipped to help both seasoned professionals and aspiring entrepreneurs make informed decisions and create products that stand out in the market.

With the right partner, brands don’t have to choose between consumer experience and a product that delivers. At VBC, we ensure you can have it all.

Reach Out

Ready to launch your very own brand of supplements for the market to consume? VBC is here to help you! We follow strict quality assurance protocols to provide the best dietary supplements for every client. Get in touch with us to learn more about our products, services, and processes.